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For example, survey respondents using GLP - 1 drugs for weight loss reported a sharp shift in their consumption from snack foods to healthy options such as proteins and fresh fruits and vegetables

FDA-approved uses of tirzepatide (Mounjaro and Zepbound): Mounjaro is an FDA-approved dual receptor agonist used to treat blood sugar levels in individuals with type 2 diabetes mellitus

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Some investigators found reduced levels of Progranulin (PGRN) in renal biopsies from DKD patients and in the kidneys of DM mice, and using PGRN-deficient mice and HG-induced human podocyte models, PGRN was found to prevent podocyte damage in DKD by promoting mitophagy and mitochondrial biogenesis [112]